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Post free for 2 Stamps open ends/or 12 Stamps in Envelope, THE MEDICAL ADVISER, on pre- JL mature decay of the system, and its speedy ser- toration; chapters on certain disorders, and the best means for their removal; the microscope as an aid to diagnosis; Marriage, its disqualiifcations; rules and prescriptions for self-treatment, &c.; illustrated with numerous cases. By Dr Walter De Roos, Holford House, Holford Square, London. W.C NOTICE TO invalids.—Although there is no denying that the Guttae Vitse are admirably adapted for all the complaints enumer- ted below, their remarkably efficacy in those cases where they have had a fair trial having been most con- clusive; still, in all long-standing or severe cases, it will be judicious to write, without delay, to Dr De Roos, Holford House, Holford Square, London, W.C. giving a minute detail as to the symptoms and dura- tion of the complaint, general health, habits, occupa- tion, age, &c., enclosing a Post-office Order for =61 Is., when advice and medicines will be forwarded per re- turn. Correspondence continued until a cure is effected. All communications considered strictly confidental. DR. DE ROOS' celebrated GUTT2E VIT.E, Or LIFE DROPS; for Spermatorrhoea, Noctur- nal Emissions, Impotency,Sexual Incapacity,Debility, Epilepsy, and all those Diseases for which Mercury, Sarsaparilla, &c., are too often employed by English Physicians to the ultimate ruin of the Sufferer's health. The GUTTJE VITÆ are the result of loug practical investigation of the remedies best adapted for these diseases. Their rich, stimulating, stomachic qualities, and, above all, their complete renovation of the nervous system, render them in every respect worthy their significant title. They may be taken without hind- rance or restraint of diet, &c., and in this respect also they may claim pre-eminence over most other adver- tised medicines. By promoting digestion—nourish- ing the constitution-enriching without inflaming the blood—bracing without stimulating the nervous sys- tem too violently-they strengthen the general habit, and restore the natural healty tone of the nervous and muscular fibres, thus enlivening and invigorating both body and mind. The GUTTÆ VITÆ have been particularly success- ful with young people who have the appearance of old age; who are pale and effeminate, and who, having an utter distaste for everything, are incapacitated for study, business, or enjoyent. Thousands of apparently hopeless cases, given up by the faculty, have been permanently cured, and have borne grateful evidence of the fact. Price 4s. 6d., lis. and 33s. of all Chemists, or direct on receipt of stamps or post-office order addressed to Dr. De Roos, Holford House, Holford Square, London, W.C. PAINS IN THE BACK.-Gravel, Lumbago, -I- Rheumatism, Gout, Flatulency, Headache, Ner- vousness, Debility, Stricture, &c. DR. DE ROOS' COMPOUND RENAL PILLS, (as their name Renal or the Kidneys, indicates), are celebrated all over the world as the safest and best Remedy for the above dangerous complaints. Discharges of any kind, and Disease of the kidneys, Bladder, and Urinary Organs generally, which, if neglected, frequently end in Stone in the Bladder, and a lingering painful death. For Depression of Spirits, Excitement, Incapacity for Society, Study or Business, Loss of Memory, Wretch- edness, Nervousness, and even Insanity itself, when (as is often the case) arising from or combined with Urinary Diseases, they are unequalled. By their salutary action on Bile and Acidity of the Stomach, they purify and promote the Renal Secretions, thereby prevent the formation of Stone, and thus establish for life the healthy functions of all these organs. Price Is. ltd., 2s. 9d., 4s. 6d., lis. and 33s. per box, with full directions through all chemists. The Genuine have the words" Walter De :Roos, London," in white letters, on the Stamp affixed to each box, by special direction of Her Majesty's Honourable commissioners, to protect the public from fraud, and to imitate which is felony and transportation. CAUTION.-Some unprincipled Vendors, when asked for Dr. De Roos' Pills, have attempted to foist other medicines or compounds of their own upon the purchaser, from which they obtain a larger profit, but which invariably entail disappointment. Ask for DR. DE ROOS' COMPOUND RENAL PILLS, and do not bo persuaded into trying anything else; but should the least difficulty occur, enclose the amount by post-office order or stamps as above, and they will be sent per return. Sold by:-Hughes, Chemist, Bangor; Roberts, Cnemist, Conway; Griffith, Chemist, High-street, Carnarvon Edwards, Chemist, Denbigh; Hughes, Chemist, Holyhead; and Moore, Chemist, Newtown; and at least one agent in almost every town but should difficulty occur, enclose the amount by Post- office order or otherwise, to Dr. De Roos, Holford House, Holford Square, London, W.C., and they will bo sent securely packed per return. NOTIOE AND CAUTION.—There being inju- I nous imitations of tlte above, sufferers should guard against the recommendation of the spurious or other articles, by dishonest vendors, who thereby obtain a larger profit. The Genuine h-ive the words"WAL- TER DE ROOS, LONDON," printed in lohite letters on the Government Stamp, BY ORDER OF HER MAJESTY'S HO:N. COMMISSIONERS, to imitate which is felony and transportation. Sold by H. Jones. A FAIR SKIN AND LOVELY COMPLEXION insured by the use of MADAME ROSALIE COUPELLE'S EAU DE PARADIS, the only certain remedy for skin diseases yet brought before the public. It is largely prescribed and used by the faculty, and whilst it per- manently eradicates tan, sallowness, pimples, freckles, small pox marks, roughness, and effectually removes discolourations it is perfectly innocuous to the skin itself. One trial will connvice the most sceptical of its marvellous effects. There are many unprincipled and trashy imitations of the above, and the public is therefore warned that none is genuine unless bearing the signature'* Rosalie Coupelle," to imitate which is a forgery. Price 2s. 9d., 4s. 6d-, and lis. per bottle through all Chemists, in the world, or direct from Madame Rosalie Coupelle, Bond-street, London, W.C., on receipt of the amount in uncut postage stamps. Sold by H. Jones. TO BE GIVEN AWAY! A new medical Work on Marriage, the cause and cure of premature decline in man, Nervous Debility, Impotency, &c., with Rules for removing certain disqualifications that destroy the happiness of wedded life, or EVER i MAN HIS OWN DOCTOR. For two stamps sufferers may avoid, the nnmerous impostors who send their boohs for nothing, publish testimonials which they write themselves, fictitious re- views from_ imaginary Journals, profess to cure diseases with instruments instead of medicines, and other absurdities as cruel as they are deceptive. A physician. 25 years extensively engaged in the treatment of debility, and the various mental and nervous affections resulting therefrom, will send free on receipt of two penny stamps to prepay postage a pamphlet containing his highly successful and only safe treatment, with all the necessary prescriptions and directions by which sufferers may cure themselves at trifling cost. Address, Mr. Lawes, Medical Publi- sher, 14, Hand Court, Holborn., London. SELF CURE NO FICTION! MARVEL UPON MARVEL! ^VTO SUFFERER NEED NOW DESPAIR, but _L3| without running- a doctor's hill or falling into the deep ditch of quackery, may safelv, speedily and economically cure himself without the knowledge of a second party. By the introduction of the new French Medicaments THEKAPION, Nos. 1, 2 and 3 a complete revolution has been wrought in this depart- ment of medical science, whilst thousands have been restored to health and happiness who for years previously had been merely dragging out a miserable existence. THERAPION No. 1 -A Sovereign Remedy for gleet and all discharges of the mucous membranes whether of the urinary or other organs. THERAPION No. 2-A Sovereign Remedy for syphilis in all its protean forms; skin diseases, and those complaints which mercury and sarsaparilla are popularly but erroneously supposed to ciire. THERAPION No. 3-A Soversign Remedy for debility, nervousness, spermatorrhoea, langour, in- capacity for marriage, distaste tor business or pleasure love of solitude, blushing, indigestion, pains in the back and head, and all those disorders which the faculty so persistently ignore, because so impotent to cure or even relieve. Price 2s. 9d., 4s. 6d., and lis., of all Chemists. In ordering the above, the purchaser should specify which number he requires. Read the new descriptive Pamphlet, sent post free for 3 stamps, by Mr. Lawe, Medical Publisher. Hand Court, Holborn. The stamp, to imitate which is felony bears the word" Therapion," in white letters, by order of HER MAJESTY S HON. COMMISSIONERS, who thereby secure tno proprietor against infringement throughout the United Kingdom and the colonies. Sold by H, Jones. MR. DAVID ROBERTS, AUCTIONEER, CORWEN, AND MR. JOHN JONES, JUNR., CHAPEL-STREET, LLANGOLLEN, Have entered into partnership as AUCTIONEERS AND APPRAISERS, And hope with strict attention to business they will be favored with the patronage of the public. All orders for the Corwen District to be addressed to Mr. David Roberts, at Corwen, and all orders for the Llangollen District to be addressed to Mr. John Jones, Junr., Chapel-street, Llangollen. "PAHAM YR WYF YN CREDU Y BIBL." Pris 4c., trwy y Post 5c. W cael gan yr awdwr, Hugh Jones, British School, -L Vron, near Llangollen. FOR STOPPING DECAYED TEETH. MESSRS. GABRIEL'S WHITE GUTTA pERCHA jgNAMEL Is. 6d. per Box. PREPARED ONLY BY MESSRS. GABRIEL, DENTISTS, London, Liverpool, and Birmingham. Also the ROYAL TOOTH POWDER. Is. 6d. and 2s. 6d. per Box. SOLD AT H. JONES, CASTLE-STREET. HARM 0 NIUMS, BEST QUALITY ONLY, EULL compass, £ 4 15s.; 3 stops, £ 5 12s.; 5 stops, £ 6 6s.; 7 stops, £ 6 15s.; 8 stops, £ 8 17s. 6d.; 10 stops, £ 11 1 Is.; &c.—Warranted, and packed free. Price list of all kinds of musical instruments post free. B. W. EDWARD TROST, GREAT EASTERN, MUSICAL INSTRUMENT WAREHOUSE, 263, WHITECHAPEL-ROAD, LONDON. PERFUMERY. H JONES, Stationer, has just received an assort- ment of New PERFUMES. Price 9d., and Is. 3d. per bottle. MR W. OWEN, JP 0 R R E 3 T EE'S A it MS, REGENT STREET, LLANGOLLEN. THE well-known and celebrated ALES from Baker's Sun Brewery, and all Spirituous Liquors supplied. AUCTIONEER AND APPRAISER. lYIR. LEWIS WILLIAMS, AUCTIONEER AND APPRAISER, DOLGELLEY AND BALA -u.

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